Manuscripts

  • Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1. LM Holt, RD Hernandez, NL Pacheco, B Torres Ceja, M Hossain, ML Olsen, eLife August 2019. DOI: 10.7554/eLife.44667
  • Glial Dysfunction in MeCP2 Deficiency Models: Implications for Rett Syndrome. U Kahanovitch, KC Patterson, RD Hernandez, ML Olsen, International Journal of Molecular Science August 2019. DOI: 10.3390/ijms20153813
  • Magnetic Cell Sorting for In Vivo and In Vitro Astrocyte, Neuron, and Microglia Analysis. Leanne M. Holt, S. Tristan Stoyanof, ML Olsen. Online, Current Protocols 2019: https://doi.org/10.1002/cpns.71
  • Adenosine signaling though A1 receptors inhibits chemosensitive neurons in the retrotrapezoid nucleus. S James, V Hawkins, B Barna, D Ruskin, S Masino, T Moreira, ML Olsen, DK Mulkey. In press, eNEURO 2019
  • AP-1 and the injury response of the GFAP gene. M Brenner M, A Messing A, ML Olsen, Journal of Neuroscience Research, October 2018: PMCID: PMC30345544
  • MeCP2 Deficiency Leads to Loss of Glial Kir4.1. U Kahanovitch, VA Cuddapah, NL Pacheco, LN Holt, DK Mulkey, AK Percy, ML Olsen, eNEURO, February 2018: PMCID: PMC5818552
  • RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome. NL Pacheco, MR Heaven, LM Holt, DK Crossman, KJ Boggio, S Shaffer, DL Flint, ML Olsen, Molecular Autism, October 2017: PMCID: PMC5655833
  • The α2β2 isoform combination dominates the astrocytic Na+ /K+ -ATPase activity and is rendered nonfunctional by the α2.G301R familial hemiplegic migraine type 2-associated mutation, A Stoica, BR Larsen, M Assentoft, R Holm, LM Holt, F Vilhardt, B Vilsen, K Lykke-Hartmann, ML Olsen, N MacAulay, Glia, August 2017, PMID: 28787093 
  • Acute Increases in Protein O-GlcNAcylation Dampen Epileptiform Activity in Hippocampus, LT Stewart, AU Khan, K Wang, D Pizarro, S Pati, SC Buckingham, ML Olsen, JC Chatham, LL McMahon, Journal of Neuroscience, July 2017, PMID: 28760863
  • Behavioral and Motor Phenotypes in a Novel Rat Model of Rett Syndrome, KC Patterson, KM Arps, VE Hawkins, DK Mulkey and ML Olsen, Human Molecular Genetics, August 2016, PMID:27329765
  • The role of glial-specific Kir4.1 in normal and pathological states of the CNS.SE Nwaobi, VA Cuddapah, KC Patterson, AC Randolph, and ML Olsen, review, Acta Neuropathologica, March 2016 PMID: 26961251
  • Novel applications of magnetic cell sorting to analyze CNS cell-type specific gene and protein expression, PLos One (2016) LM Holt and ML Olsen, Feb 26;11(2) PMID 26919701
  • Emerging insight into the critical role of astrocyte ion channels in homeostasis and neuron-glia signaling. ML Olsen*, B Khahk, S Skatchkov, Z Min, N Rouach, Journal of Neuroscience (2015) 14;35(41):13827-35, *Corresponding Author PMCID PMC4604221
  • MECP2’s role in regulating neural activity: pathophysiological perspectives. VA Cuddapah, Nwaobi, SE, AK Percy, and ML Olsen, Degenerative Neurological and Neuromuscular Disease (2015) 5:103-116
  • Correlating gene-specific DNA methylation changes with expression and transcriptional activity of astrocytic KCNJ10 (Kir4.1), SE Nwaobi and ML Olsen, Journal of Visualized Experiments (2015) Sep(26)103 PMID 26436772
  • Elevated GFAP induces astrocyte dysfunction in caudal brain regions: a potential mechanism for hindbrain involved symptoms in type II Alexander Disease, HR Minkel, TZ Anwer, KM Arps, M Brenner, ML Olsen, Glia (2015) Dec;63(12)2285-97        PMID:26190408
  • Insufficient GLT-1 Glutamate Transport and Altered Astrocyte Biophysical Properties Contributes to Hyperexcitability in Cortical Dysplasia,  SL Campbell, JJ Hablitz and ML Olsen, Frontiers in Molecular Neuroscience (2014) Dec 17;8:425 PMID: 25565960
  • Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington’s disease model mice, X. Tong, Y Ao, GC Faas, SE Nwaobi, J Xu, MD Haustein, MA Anderson, I Mody, ML Olsen, MV Sofroniew, BS Khakh, Nature Neuroscience (2014) May;17(5):694-703 , 2014 PMID:24686787
  • Methyl-CpG-binding protein 2 (MEPC2) mutation type is associated with disease severity in Rett Syndrome, VA Cuddapah, RB Pillai, KV Shekar, JB Lane, KJ Motil, SA Skinner, G McGwin, DC Tarquinio5, DG Glaze, WE Kaufmann, AK Percy, JL Neul, ML Olsen, Journal of Medical Genetics (2014) Mar;51(3):152-8 2014 *This article was featured as editor’s choice PMID 24399845
  • DNA methylation is a critical regulator of Kir4.1 in CNS development, SE Nwaobi, SR Peramsetty, E Lin and ML Olsen, Glia (2014) Mar;62(3):411-27, 2014 PMID:24415225
  • Development and validation of fluorescence- and automated patch clamp-based functional assays for the inward rectifier potassium channel Kir4.1, R Raphemot, R Kadakia, ML Olsen, S Banerjee, E Days, SS Smith, CD Weaver and JS Denton. Assay and Drug Development Technologies (2013) Nov-Dec;11(9-10):532-43 PMID: 24266659
  • Spinal Cord Injury in vivo Causes Wide-Spread, Persistent Loss of Kir4.1 and GLT-1: Potential Benefits of Treatment with 17-beta Estradiol, ML Olsen, SL Campbell, CL Floyd, H Sontheimer, Brain (2010) 133(Pt 4):1013-25 PMID: 20375134
  • Functional Implications for Kir4.1 Channels in Glial Biology: From K+ Buffering to Cell Differentiation, ML Olsen and H Sontheimer, Journal of Neurochemistry (2008) 107, 589–601 PMID:18691387
  • ClC3 Is a Critical Regulator of Cell Cycle in Normal and Malignant Cells, CM Habela, ML Olsen and H Sontheimer, Journal of Neuroscience (2008) 28(37):9205-17 PMID: 18784301
  • BK Channels are Coupled to IP3-receptors via Lipid Rafts: a Novel Mechanism for Coupling [Ca2+]i to Channel Activation, AK Weaver, ML Olsen, MB McFerrin and H Sontheimer, Journal of Biological Chemistry (2007) 26;282(43):31558-68 PMID: 17711864
  • Differential Distribution of Kir4.1 in Spinal Cord Astrocytes Suggests Regional Differences in K+ Homeostasis, ML Olsen, SL Campbell and H Sontheimer, Journal of Neurophysiology (2007) 98(2):786-93 PMCID: 2040512
  • Functional Expression of Kir4.1 Channels in Spinal Cord Astrocytes, ML Olsen, H Higashimori, SL Campbell, JJ Hablitz and H Sontheimer, Glia (2006) 53(5):516-28, cover art PMCID: 2553202
  • Modulation of Glioma BK (gBK) Channels via erbB2, ML Olsen, AK Weaver, P Ritch, H Sontheimer, Journal of Neuroscience Research (2005) 15;81(2):179-89 PMID: 15948146
  • Mislocalization of Kir Channels in Malignant Glia, ML Olsen, H. Sontheimer, Glia (2004) 46:63-73, 200, cover art PMCID: 2548404
  • Expression of Voltage-Gated Chloride Channels in Human Glioma Cells, ML Olsen, S. Schade, S.A. Lyons, M.D. Amaral, H. Sontheimer, Journal of Neuroscience (2003) 23(13)5572-5582 PMID: 12843258

Book Chapters

  • Voltage-Gated Ion Channels in Glial Cells, ML Olsen, H Sontheimer. Neuroglia, 2nd Edition, Oxford University Press, pp112-130, 2004
  • Whole-Cell Patch Clamp Recordings, Patch-Clamp Analysis: Advanced Techniques, Second Edition, H Sontheimer and ML Olsen. Humana Press, pp35-68, 2008
  • Ionic Channels in Glia. ML Olsen and H Sontheimer, Encyclopedia of Neuroscience, Oxford: Academic Press, volume 5, pp. 237-247. 2009 book cover art
  • Potassium Channel Function in Astrocytes, Astrocytes: Methods and Protocols, ML Olsen. Humana Press, Invited Review, ed. R. Milner, Springer Press, NY, 2012
  • Ionic Channels in Glia. Encyclopedia of Neuroscience, H Sontheimer and ML Olsen, Oxford: Academic Press, Invited update,  2015
  • LM Holt and ML Olsen, The role of astrocytes in synaptic plasticity, learning and memory. Mechanism of Memory, Chapter 15, Third Edition, Academic Press, invited, in press, 2019